Bactericidal zotsatira za hyperbaric oxygen therapy mu kuvulala kwamoto

Mawu Oyamba

Kuvulala kwamoto kumachitika kawirikawiri pakagwa mwadzidzidzi ndipo nthawi zambiri kumakhala doko lolowera tizilombo toyambitsa matenda.Kuvulala kopitilira 450,000 kumachitika chaka chilichonse kupha pafupifupi 3,400 ku United States.Kuchuluka kwa kuvulala kwamoto ku Indonesia ndi 0.7% mu 2013. Zoposa theka la izi Malinga ndi maphunziro angapo okhudza kugwiritsa ntchito odwala adachiritsidwa ndi matenda a bakiteriya, ena mwa iwo anali osagonjetsedwa ndi maantibayotiki ena.Kugwiritsahyperbaric oxygen therapy(HBOT) yochizira kuyaka imakhala ndi zotsatira zabwino zingapo kuphatikiza kuyang'anira matenda a bakiteriya, komanso kufulumizitsa machiritso a bala.Chifukwa chake, phunziroli likufuna kutsimikizira mphamvu ya HBOT poletsa kukula kwa mabakiteriya.

Njira

Uwu ndi kafukufuku woyeserera wa akalulu pogwiritsa ntchito kapangidwe ka gulu lowongolera pambuyo pa mayeso.Akalulu a 38 anapatsidwa kutentha kwa digiri yachiwiri pamapewa ndi mbale yachitsulo yomwe yatenthedwa kale kwa 3 min.Zikhalidwe za mabakiteriya zidatengedwa pamasiku 5 ndi 10 mutakumana ndi zowotcha.Zitsanzozi zidagawidwa m'magulu awiri, HBOT ndi control.Kusanthula kwachiwerengero kunachitika pogwiritsa ntchito njira ya Mann-Whitney U.

Zotsatira

Mabakiteriya a gram-negative anali omwe amapezeka kawirikawiri m'magulu onsewa.Citrobacter freundi anali mabakiteriya ambiri a Gram-negative (34%) omwe amapezeka muzotsatira zamagulu onsewa.

Mosiyana ndi gulu lolamulira, panalibe kukula kwa bakiteriya komwe kunapezeka mu zotsatira za chikhalidwe cha gulu la HBOT, (0%) vs (58%).Kuchepetsa kwakukulu kwa kukula kwa mabakiteriya kunawonedwa mu gulu la HBOT (69%) poyerekeza ndi gulu lolamulira (5%).Miyezo ya mabakiteriya idayima mu akalulu a 6 (31%) mu gulu la HBOT ndi akalulu 7 (37%) mu gulu lolamulira.Pazonse, panali kuchepa kwa mabakiteriya ocheperako mu gulu lachipatala la HBOT poyerekeza ndi gulu lolamulira (p <0.001).

Mapeto

Kuwongolera kwa HBOT kumatha kuchepetsa kwambiri kukula kwa bakiteriya pakuvulala kwamoto.